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Utskrift från Malmö universitet - $.mah.se

Sebastian Björklund
Associate Professor

My Research

The outermost skin layer represents the main skin barrier and this layer is usually referred to as the stratum corneum (SC). The SC represents a thin membrane (ca. 1/50 of a printing paper sheet) that is composed of corneocytes (dead cells), which are embedded in an extracellular lipid lamellae. Traditionally, the SC is thought of as non-viable tissue. While this is true, the SC is a dynamic structure in which several enzymes are embedded in a functional state, and these enzymes require a certain amount of liquid water and flexibility of the surrounding matrix.

At present, it is not clear why dry skin and common skin diseases develop in most cases, which is likely due to the complex interplay between overall health status, nutritional aspects, physical exercise, external parameters, such as air pollution, UVR, relative humidity (RH), temperature, etc. Likewise, treatment of wounds, in particular chronic wounds and diabetic foot ulcers, for optimized healing is far from being understood. Considering the complexity of the skin organ, in combination with the presence of multiple external parameters that may affect skin's health status, it is inherently challenging to assign a precise mechanism why even the most common skin diseases develops.

The overall goal of my research is to advance the current understanding of key processes required to maintain a proper skin barrier, associated with a healthy skin organ. In brief, this is achieved by combining well-defined and relatively simple experimental conditions with the complex biological skin barrier system to connect the molecular properties of the skin barrier with its macroscopic barrier properties.


Research centres

Biofilms Research Center for Biointerfaces pil show

Research platforms

Skin and Wound Care pil show

Faculties and departments

Department of Biomedical Science pil show
Faculty of Health and Society pil show

Contact details

E-mail:sebastian.bjorklund@mau.se
Telephone:040-6657891
Visiting address: Per Albin Hanssons väg 35, Forskaren, Plan 3
Mobile:0725-464824
Fax:
Postal address:Malmö universitet, 205 06 Malmö
Delivery address:73

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  • Publications

  • Last publications from Malmö University Electronic Publishing.

    2020 | Artikel i tidskrift
    Skin hydration dynamics investigated by electrical impedance techniques in vivo and in vitro.
    Morin Maxim, Ruzgas Tautgirdas, Svedenhag Per, Anderson Christopher D, Ollmar Stig, Engblom Johan, Björklund Sebastian

    2020 | Artikel i tidskrift
    Characterization of nano-layered solid-contact ion selective electrodes by simultaneous potentiometry and quartz crystal microbalance with dissipation.
    Krikstolaityte Vida, Ding Ruiyu, Ruzgas Tautgirdas, Björklund Sebastian, Lisak Grzegorz

    2020 | Artikel i tidskrift
    Design and use of model membranes to study biomolecular interactions using complementary surface-sensitive techniques.
    Clifton Luke A, Campbell Richard A, Sebastiani Federica, Campos-Terán José, Gonzalez-Martinez Juan F, Björklund Sebastian, Sotres Javier, Cárdenas Marité

    2019 | Artikel i tidskrift
    New concepts for transdermal delivery of oxygen based on catalase biochemical reactions studied by oxygen electrode amperometry
    Hernández Aura Rocio, Boutonnet Marine, Svensson Birgitta, Butler Eile, Lood Rolf, Blom Kristina, Vallejo Bibiana, Anderson Chris, Engblom Johan, Ruzgas Tautgirdas, Björklund Sebastian

    2019 | Artikel i tidskrift
    The Effect of UVB Irradiation and Oxidative Stress on the Skin Barrier
    Hernández Aura Rocio, Vallejo Bibiana, Ruzgas Tautgirdas, Björklund Sebastian

    Länk till alla publikationer i DIVA.
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Malmö högskola
Hälsa och samhälle
Biomedicinsk vetenskap
WORK 205 06 Malmö Sverige Per Albin Hanssons väg 35
Postadress: 
  Malmö universitet  
205 06 Malmö
  
  Besök: 
  , rum Forskaren, Plan 3, Per Albin Hanssons väg 35, Malmö

			
work 040-6657891 cell 0725-464824
Sebastian Björklund